Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3396060 | 0.89 | CYP1A2 (0.55) | SNCACYP1A2ATMTDP1MAPT | |
| SCHEMBL7418264 | 0.81 | CYP1A2 (0.57) | SNCACYP1A2TDP1MAPTALDH1A1 | |
| SCHEMBL9113 | 0.80 | AKR1B1 (0.58) | CYP1A2TDP1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL2531929 | 0.78 | AKR1B1 (0.56) | CYP1A2IDO1 | |
| SCHEMBL2989578 | 0.77 | CYP1A2 (0.69) | SNCACYP1A2ATMTDP1MAPT | |
| SCHEMBL2989584 | 0.77 | CYP1A2 (0.69) | SNCACYP1A2ATMTDP1MAPT | |
| SCHEMBL9651648 | 0.77 | MAOA (0.59) | SNCAATMTDP1MAPTALDH1A1 | |
| SCHEMBL20616356 | 0.76 | AKR1B1 (0.64) | CYP1A2TDP1MAPTKDM4EHTT | |
| SCHEMBL23200508 | 0.76 | ATM (0.51) | SNCACYP1A2ATMTDP1MAPT | |
| SCHEMBL10509624 | 0.76 | TDP1 (0.51) | SNCACYP1A2IDO1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546145-A1 | HETEROCYCLIC SUBSTITUTED PIPERAZINES FOR THE TREATMENT OF SCHIZOPHRENIA | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004029048-A1 | HETEROCYCLIC SUBSTITUTED PIPERAZINES FOR THE TREATMENT OF SCHIZOPHRENIA | WARNER-LAMBERT COMPANY LLC (US) | 2004-04-08 | — | — | WO | disclosed |