Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21083725 | 0.85 | CYP3A4 (0.58) | HIF1ACYP2C9TSHRCYP3A4CYP2D6 | |
| SCHEMBL30593971 | 0.74 | CHKA (0.55) | HIF1ACYP2C9TSHRCYP3A4CYP2D6 | |
| SCHEMBL23288947 | 0.73 | KCNH2 (0.43) | CYP3A4CYP2D6CYP2C19ALDH1A1ITGB3 | |
| SCHEMBL15217514 | 0.72 | ADRA2C (0.47) | CYP3A4CYP2C19ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL29514514 | 0.72 | CYP2C9 (0.59) | HIF1ACYP2C9TSHRCYP3A4CYP2D6 | |
| SCHEMBL38663059 | 0.72 | HIF1A (0.76) | HIF1ACYP2C9TSHRCYP3A4CYP2D6 | |
| SCHEMBL3315322 | 0.71 | CYP2C9 (0.51) | HIF1ACYP2C9TSHRCYP3A4CYP2D6 | |
| SCHEMBL6189372 | 0.71 | F10 (0.54) | HIF1ACYP2C9TSHRCYP3A4CYP2D6 | |
| Methane SCHEMBL4241075 | 0.71 | CHKA (0.55) | HIF1ACYP2C9TSHRCYP3A4CYP2D6 | |
| SCHEMBL23875490 | 0.70 | CHKA (0.59) | HIF1ACYP2C9TSHRCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070714-A9 | AMIDINE COMPOUNDS | JAPAN TOBACCO INC. (JP) | 2005-10-19 | — | — | EP | disclosed |
| EP-1070714-B1 | AMIDINE COMPOUNDS | JAPAN TOBACCO INC (JP) | 2004-08-04 | — | — | EP | disclosed |
| US-20040006099-A1 | Amidine compounds | JAPAN TOBACCO INC. | 2004-01-08 | — | — | US | disclosed |
| US-6562828-B1 | Novel amidine compound having a blood coagulation factor Xa inhibitory activity | JAPAN TOBACCO INC. (JP) | 2003-05-13 | — | — | US | disclosed |
| CN-1305470-A | Amidine compounds | JAPAN TOBACCO INC (JP) | 2001-07-25 | — | — | CN | disclosed |
| EP-1070714-A1 | AMIDINE COMPOUNDS | JAPAN TOBACCO INC. (JP) | 2001-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006099-A1 | Amidine compounds | F2, SERPINC1, F12 | HIF1A 681/4885CYP2C9 92/4885TSHR 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.