Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6020 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL478150 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL478149 | 0.94 | — | — | |
| Bromide SCHEMBL560670 | 0.92 | — | — | |
| SCHEMBL31112230 | 0.83 | LOXL2 (0.41) | — | |
| Bromide SCHEMBL3395799 | 0.78 | LOXL2 (0.54) | — | |
| Benzyl Bromide SCHEMBL28307155 | 0.78 | ALDH1A1 (0.74) | — | |
| Bromide SCHEMBL29980639 | 0.77 | ALDH1A1 (0.62) | — | |
| Benzyl Bromide SCHEMBL365150 | 0.76 | TSHR (0.70) | — | |
| SCHEMBL6611097 | 0.75 | MEN1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1051 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190169227-A1 | METHOD FOR PRODUCTION OF NOVEL GALETERONE ANALOGS AND USES THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2019-06-06 | — | — | US | claimed |
| EP-3474848-A1 | METHOD FOR PRODUCTION OF NOVEL GALETERONE ANALOGS AND USES THEREOF | University of Maryland, Baltimore (US) | 2019-05-01 | — | — | EP | claimed |
| WO-2017223320-A1 | METHOD FOR PRODUCTION OF NOVEL GALETERONE ANALOGS AND USES THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2017-12-28 | — | — | WO | claimed |
| EP-2397478-A1 | 1,3-diaryl substituted ureas as modulators of kinase activity. | CGI Pharmaceuticals, Inc. (US) | 2011-12-21 | — | — | EP | claimed |
| EP-4737443-A1 | SALT-INDUCIBLE KINASE INHIBITORY COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Tanabe Pharma Corporation (JP) | 2026-05-06 | — | — | EP | disclosed |
| US-12617769-B2 | Chemical compound as thyroid hormone beta receptor agonist and use thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2026-05-05 | — | — | US | disclosed |
| EP-4724431-A1 | BENZOFURAN DERIVATIVES AS SIK INHIBITORS AND USE THEREOF | Beone Medicines I GmbH (CH) | 2026-04-15 | — | — | EP | disclosed |
| US-20260085053-A1 | BENZOFURAN DERIVATIVES AS SIK INHIBITORS AND THE USE THEREOF | BEONE MEDICINES I GMBH (CH) | 2026-03-26 | — | — | US | disclosed |
| EP-3814356-B1 | TRIAZOLOTRIAZINE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS | ZHEJIANG VIMGREEN PHARMACEUTICALS LTD (CN) | 2026-03-11 | — | — | EP | disclosed |
| US-12570607-B2 | Compound as cyclin-dependent kinase 9 inhibitor and use thereof | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) | 2026-03-10 | — | — | US | disclosed |
| US-20260062387-A1 | SALT-INDUCIBLE KINASE INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2026-03-05 | — | — | US | disclosed |
| US-12559454-B2 | Benzenesulfonamide derivatives and uses thereof | 2692372 ONTARIO, INC. (CA) | 2026-02-24 | — | — | US | disclosed |
| US-5962458-A | ANGIOGENESIS INHIBITORS, ANTICANCER AGENTS, ANTIDIABETIC AGENTS, SKIN DISORDERS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, VISION DEFECTS | ZENECA LIMITED (GB) | 1999-10-05 | — | — | US | disclosed |
| WO-1999001428-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-01-14 | — | — | WO | disclosed |
| EP-0873319-A1 | QUINAZOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997022596-A1 | QUINAZOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1997-06-26 | — | — | WO | disclosed |
| US-4535084-A | ANTIARTHRITIC, ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1985-08-13 | — | — | US | disclosed |
| US-4500535-A | ANTIARTHRITIC AGENTS | PFIZER INC. (US) | 1985-02-19 | — | — | US | disclosed |
| US-4371696-A | ANTIINFLAMMATORY AND IMMUNOREGULATORY AGENTS | PFIZER INC. (US) | 1983-02-01 | — | — | US | disclosed |
| US-4246263-A | ANTIARTHRITIC AGENTS | PFIZER INC. (US) | 1981-01-20 | — | — | US | disclosed |