Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617168 | 0.85 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL3843531 | 0.82 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL6649037 | 0.82 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL3845342 | 0.82 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL6092163 | 0.82 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL4960335 | 0.82 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL3839119 | 0.81 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL3842329 | 0.81 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL6643610 | 0.80 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL3842234 | 0.80 | CRHR1 (0.46) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116444-A1 | Substituted 1,4-pyrazine derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-17 | — | — | US | claimed |
| EP-1539736-A1 | SUBSTITUTED 1,4-PYRAZINE DERIVATIVES | Pharmacia & Upjohn Company LLC (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040116444-A1 | Substituted 1,4-pyrazine derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-17 | — | — | US | disclosed |
| WO-2004024719-A1 | SUBSTITUTED 1,4-PYRAZINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-25 | — | — | WO | disclosed |