Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 6/20 | 0.57 |
| ▸ | HTR2C | P28335 | 4/20 | 0.55 |
| ▸ | HTR2B | P41595 | 4/20 | 0.55 |
| ▸ | HTR2A | P28223 | 3/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17583866 | 0.87 | HTR2C (0.51) | PNMTHTR2CHTR2BHTR2AASIC3 | |
| SCHEMBL5022472 | 0.81 | PNMT (0.59) | PNMTHTR2CHTR2BHTR2AADRA2A | |
| SCHEMBL6189510 | 0.80 | HTR2C (0.79) | PNMTHTR2CHTR2BHTR2AADRA2A | |
| SCHEMBL16210119 | 0.80 | PNMT (0.57) | PNMTHTR2CHTR2BHTR2AADRA2A | |
| SCHEMBL11737280 | 0.77 | PNMT (0.57) | PNMTHTR2CHTR2BHTR2AADRA2A | |
| SCHEMBL14925193 | 0.76 | PNMT (0.54) | PNMTHTR2CHTR2BHTR2AADRA2A | |
| SCHEMBL915092 | 0.76 | PNMT (0.69) | PNMTHTR2CHTR2BHTR2ACD274 | |
| SCHEMBL22102585 | 0.75 | HTR2C (0.41) | HTR2CHTR2BHTR2A | |
| SCHEMBL6168691 | 0.75 | HTR2A (0.41) | HTR2CHTR2BHTR2A | |
| SCHEMBL29660392 | 0.75 | HTR2A (0.41) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651955-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153947-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2024-07-25 | — | — | WO | disclosed |
| EP-0994862-B1 | SULPHONAMIDE DERIVATIVES BEING 5-HT6 RECEPTOR ANTAGONISTS AND PROCESS FOR THEIR PREPARATION | SMITHKLINE BEECHAM PLC (GB) | 2005-06-01 | — | — | EP | disclosed |