Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.79 |
| ▸ | HTR2B | P41595 | 6/20 | 0.79 |
| ▸ | HTR2A | P28223 | 5/20 | 0.79 |
| ▸ | PNMT | P11086 | 6/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11322725 | 0.90 | HTR2C (0.65) | HTR2CHTR2BHTR2APNMTADRA2A | |
| SCHEMBL21762550 | 0.88 | HTR2C (1.00) | HTR2CHTR2BHTR2APNMTADRA2A | |
| SCHEMBL3776258 | 0.87 | HTR2C (0.79) | HTR2CHTR2BHTR2APNMTADRA2A | |
| Hydrochloric Acid SCHEMBL21753252 | 0.87 | HTR2C (0.97) | HTR2CHTR2BHTR2APNMTADRA2A | |
| SCHEMBL30471722 | 0.87 | HTR2C (0.79) | HTR2CHTR2BHTR2APNMTADRA2A | |
| SCHEMBL31463205 | 0.84 | HTR2C (0.60) | HTR2CHTR2BHTR2APNMTADRA2A | |
| Hydrochloric Acid SCHEMBL31084068 | 0.83 | HTR2C (0.58) | HTR2CHTR2BHTR2APNMTADRA2A | |
| SCHEMBL5022472 | 0.81 | PNMT (0.59) | HTR2CHTR2BHTR2APNMTADRA2A | |
| SCHEMBL6187571 | 0.80 | PNMT (0.57) | HTR2CHTR2BHTR2APNMTADRA2A | |
| SCHEMBL16210119 | 0.80 | PNMT (0.57) | HTR2CHTR2BHTR2APNMTADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994862-B1 | SULPHONAMIDE DERIVATIVES BEING 5-HT6 RECEPTOR ANTAGONISTS AND PROCESS FOR THEIR PREPARATION | SMITHKLINE BEECHAM PLC (GB) | 2005-06-01 | — | — | EP | disclosed |