Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 15/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186844 | 0.91 | F10 (0.56) | GPR119F10 | |
| SCHEMBL6186841 | 0.91 | F10 (0.56) | GPR119F10 | |
| SCHEMBL6186585 | 0.85 | F10 (0.53) | GPR119F10CETP | |
| SCHEMBL6186837 | 0.85 | GPR119 (0.41) | GPR119F10PRMT5ACSL1ALK | |
| SCHEMBL6190950 | 0.84 | GPR119 (0.56) | GPR119F10ACSL1ALKCETP | |
| SCHEMBL6186994 | 0.82 | F10 (0.51) | GPR119F10CETP | |
| SCHEMBL6188847 | 0.81 | GPR119 (0.53) | GPR119F10ACSL1ALKCETP | |
| SCHEMBL6191999 | 0.80 | GPR119 (0.53) | GPR119F10PRMT5ACSL1ALK | |
| SCHEMBL6190762 | 0.78 | F10 (0.64) | GPR119F10CETP | |
| SCHEMBL6190756 | 0.78 | F10 (0.64) | GPR119F10CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070714-A9 | AMIDINE COMPOUNDS | JAPAN TOBACCO INC. (JP) | 2005-10-19 | — | — | EP | disclosed |
| US-20040006099-A1 | Amidine compounds | JAPAN TOBACCO INC. | 2004-01-08 | — | — | US | disclosed |
| US-6562828-B1 | Novel amidine compound having a blood coagulation factor Xa inhibitory activity | JAPAN TOBACCO INC. (JP) | 2003-05-13 | — | — | US | disclosed |
| EP-1070714-A1 | AMIDINE COMPOUNDS | JAPAN TOBACCO INC. (JP) | 2001-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006099-A1 | Amidine compounds | F2, SERPINC1, F12 | GPR119 2900/4885F10 16/4885PRMT5 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.