Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17489048 | 0.84 | KDM4E (0.61) | TSHRKDM4EALOX15ACMSDTDP1 | |
| SCHEMBL19880446 | 0.82 | PIM1 (0.43) | ALDH1A1TSHRKDM4EALOX15ACMSD | |
| SCHEMBL455687 | 0.80 | KDM4E (0.59) | ALDH1A1TSHRKDM4EALOX15ACMSD | |
| SCHEMBL9364954 | 0.80 | HSP90AA1 (0.32) | TSHRKDM4EALOX15ACMSDTDP1 | |
| SCHEMBL12125682 | 0.79 | FFAR4 (0.41) | ALDH1A1TSHRKDM4EALOX15ACMSD | |
| SCHEMBL20049344 | 0.79 | MAPT (0.49) | ALDH1A1TSHRKDM4ECYP1A2GRM5 | |
| SCHEMBL14733165 | 0.79 | IRAK4 (0.35) | ALDH1A1P2RX7IRAK4 | |
| SCHEMBL6641842 | 0.78 | KDM4E (0.56) | ALDH1A1TSHRKDM4EALOX15ACMSD | |
| SCHEMBL247491 | 0.77 | P2RX7 (0.60) | ALDH1A1TSHRKDM4EALOX15ACMSD | |
| SCHEMBL29590328 | 0.77 | P2RX7 (0.60) | ALDH1A1TSHRKDM4EALOX15ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572655-A2 | NOVEL ARYLHETEROALKYLAMINE DERIVATIVES | AstraZeneca AB (SE) | 2005-09-14 | — | — | EP | disclosed |
| WO-2002090332-A2 | NOVEL AEYLHETEROALKYLAMINΕ DERIVATIVES | ASTRAZENECA AB (SE) | 2002-11-14 | — | — | WO | disclosed |