Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | FADS1 | O60427 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6189844 | 0.89 | RECQL (0.48) | RECQLKCNA5NOS2IDO1KDM4E | |
| SCHEMBL31444308 | 0.83 | KCNA5 (0.51) | KCNA5KDM4AKDM4EALDH1A1RCE1 | |
| SCHEMBL21987969 | 0.83 | IDO1 (0.48) | KCNA5NOS2KDM4AIDO1KDM4E | |
| SCHEMBL6191669 | 0.82 | GAA (0.50) | RECQLNOS2GAAHDAC1HDAC10 | |
| SCHEMBL700928 | 0.82 | IDO1 (0.50) | KCNA5KDM4AIDO1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL709884 | 0.81 | IDO1 (0.49) | KCNA5KDM4AIDO1KDM4EALDH1A1 | |
| SCHEMBL21987982 | 0.80 | IDO1 (0.51) | KCNA5KDM4AIDO1KDM4EALDH1A1 | |
| SCHEMBL6190237 | 0.80 | GAA (0.43) | RECQLNOS2KDM4EALDH1A1HPGD | |
| SCHEMBL6189254 | 0.79 | KCNA5 (0.41) | KCNA5NOS2KDM4AIDO1KDM4E | |
| SCHEMBL6190137 | 0.79 | KCNA5 (0.44) | KCNA5KDM4AIDO1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979227-B1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA PHARMACEUTICAL (JP) | 2005-11-16 | — | — | EP | disclosed |
| US-6352982-B1 | TREATING DIABETES, OBESITY, OR INVETERATE DIARRHEA IN A MAMMAL WHICH COMPRISES ADMINISTERING AN EFFECTIVE AMOUNT OF A COMPOUND OF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |