Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 1/20 | 0.50 |
| ▸ | F12 | P00748 | 12/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.45 |
| ▸ | F2 | P00734 | 6/20 | 0.45 |
| ▸ | PLG | P00747 | 6/20 | 0.45 |
| ▸ | F10 | P00742 | 3/20 | 0.45 |
| ▸ | C1R | P00736 | 2/20 | 0.45 |
| ▸ | KLK1 | P06870 | 2/20 | 0.45 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.45 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | HPN | P05981 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | C1S | P09871 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698009 | 0.79 | FTO (0.59) | FTOF12PRSS1F2PLG | |
| SCHEMBL7341905 | 0.77 | F12 (0.57) | FTOF12PRSS1F2PLG | |
| SCHEMBL7336993 | 0.77 | FTO (0.62) | FTOF12PRSS1F2PLG | |
| Nafamostat SCHEMBL29832433 | 0.74 | FTO (0.70) | FTOF12PRSS1F2PLG | |
| Nafamostat SCHEMBL564665 | 0.74 | FTO (0.70) | FTOF12PRSS1F2PLG | |
| Nafamostat SCHEMBL874941 | 0.74 | FTO (0.64) | FTOF12PRSS1F2PLG | |
| SCHEMBL7340854 | 0.74 | F12 (0.55) | FTOF12PRSS1F2PLG | |
| Nafamostat SCHEMBL1568755 | 0.74 | FTO (0.70) | FTOF12PRSS1F2PLG | |
| SCHEMBL7350024 | 0.73 | FTO (0.62) | FTOF12PRSS1F2PLG | |
| SCHEMBL7341009 | 0.72 | F12 (0.50) | FTOF12PRSS1F2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8790885-B2 | Coagulogen raw material, process for producing the same, and method and apparatus for measuring physiologically active substance of biological origin using the same | KOWA COMPANY, LTD. (JP) | 2014-07-29 | — | — | US | disclosed |
| US-8211651-B2 | Method for measuring endotoxin and reagent kit for measuring endotoxin | KOWA COMPANY, LTD. (JP) | 2012-07-03 | — | — | US | disclosed |
| US-20120040385-A1 | COAGULOGEN RAW MATERIAL, PROCESS FOR PRODUCING THE SAME, AND METHOD AND APPARATUS FOR MEASURING PHYSIOLOGICALLY ACTIVE SUBSTANCE OF BIOLOGICAL ORIGIN USING THE SAME | KOWA COMPANY, LTD. (JP) | 2012-02-16 | — | — | US | disclosed |
| US-20110201015-A1 | METHOD FOR MEASURING ENDOTOXIN AND REAGENT KIT FOR MEASURING ENDOTOXIN | KOWA COMPANY, LTD. (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2233927-A1 | METHOD FOR MEASURING ENDOTOXIN AND REAGENT KIT FOR MEASURING ENDOTOXIN | Kowa Company, Ltd. (JP) | 2010-09-29 | — | — | EP | disclosed |
| EP-0765339-A1 | 3-AMINO-2-OXO-1-PIPERIDINEACETIC DERIVATIVES CONTAINING AN ARGININE MIMIC AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1997-04-02 | — | — | EP | disclosed |
| WO-1995035313-A1 | 3-AMINO-2-OXO-1-PIPERIDINEACETIC DERIVATIVES CONTAINING AN ARGININE MIMIC AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1995-12-28 | — | — | WO | disclosed |
| US-5238964-A | P-Guanidinobenzoic acid derivatives | TORII & CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |