Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | ULK1 | O75385 | 1/20 | 0.47 |
| ▸ | ITK | Q08881 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | STK17B | O94768 | 1/20 | 0.46 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6185392 | 0.99 | MAOA (0.49) | MAOAMAOBPOLBSMN1; SMN2GRM4 | |
| SCHEMBL6187015 | 0.97 | ULK1 (0.49) | MAOAMAOBPOLBSMN1; SMN2GRM4 | |
| SCHEMBL6188504 | 0.89 | GRM4 (0.51) | MAOAMAOBPOLBSMN1; SMN2GRM4 | |
| SCHEMBL6188606 | 0.88 | MAOA (0.55) | MAOAMAOBSMN1; SMN2ITKNPSR1 | |
| SCHEMBL6185134 | 0.87 | MAOA (0.54) | MAOAMAOBSMN1; SMN2GRM4ITK | |
| SCHEMBL6189495 | 0.87 | PARP1 (0.45) | MAOAMAOBPOLBULK1MTNR1A | |
| SCHEMBL6189454 | 0.87 | MAOA (0.53) | MAOAMAOBPOLBSMN1; SMN2ULK1 | |
| SCHEMBL6189592 | 0.85 | MAOA (0.51) | MAOAMAOBPOLBSMN1; SMN2ULK1 | |
| SCHEMBL6187132 | 0.85 | MAOA (0.50) | MAOAMAOBPOLBSMN1; SMN2ULK1 | |
| SCHEMBL6186285 | 0.84 | MAOA (0.49) | MAOAMAOBPOLBSMN1; SMN2ULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554271-A1 | SUBSTITUTED INDOLES AND THEIR USE AS HCV INHIBITORS | Rigel Pharmaceuticals, Inc. (US) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004035571-A1 | SUBSTITUTED INDOLES AND THEIR USE AS HCV INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2004-04-29 | — | — | WO | disclosed |