SCHEMBL6190

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7133	0.92	PPARG (0.38)	PPARGPPARALPAR1LPAR2LPAR3
	SCHEMBL7117	0.91	LPAR1 (0.39)	PPARGLPAR1LPAR2LPAR3MMP12
	SCHEMBL6389	0.88	LPAR1 (0.39)	PPARGLPAR1LPAR2LPAR3MMP12
	SCHEMBL6588	0.88	PTGS2 (0.45)	LPAR1LPAR2LPAR3MMP12MMP13
	SCHEMBL7041	0.85	LPAR1 (0.37)	LPAR1LPAR2LPAR3MMP12MMP13
	SCHEMBL7260	0.84	PTGER1 (0.50)	LPAR1LPAR2LPAR3MMP12MMP13
	SCHEMBL18597843	0.84	MMP12 (0.41)	LPAR1LPAR2LPAR3MMP12MMP13
	SCHEMBL6390	0.83	LPAR1 (0.39)	LPAR1LPAR2LPAR3MMP12MMP13
	SCHEMBL7358	0.82	LPAR1 (0.40)	PPARGPPARALPAR1LPAR2LPAR3
	SCHEMBL7024	0.82	LPAR1 (0.48)	LPAR1LPAR2LPAR3MMP12MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.