Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.64 |
| ▸ | RELA | Q04206 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | ACP1 | P24666 | 1/20 | 0.63 |
| ▸ | NCS1 | P62166 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29483685 | 1.00 | CSNK1D (0.64) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| Ethylene SCHEMBL8167289 | 0.84 | CSNK1D (0.69) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL4862601 | 0.81 | POLB (0.74) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL29485044 | 0.81 | DYRK1A (0.69) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL29282910 | 0.81 | DYRK1A (0.69) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL29485043 | 0.81 | DYRK1A (0.69) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL6190386 | 0.81 | ADORA1 (0.65) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL7933388 | 0.81 | HDAC3 (0.71) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL4858014 | 0.81 | CSNK1D (0.69) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL6206186 | 0.81 | RAB9A (0.72) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341368-B | Method for synthesizing alpha-fluorinated thioacrylamide derivative | 温州大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-112341368-A | Method for synthesizing alpha-fluorinated thioacrylamide derivative | 温州大学 | 2021-02-09 | — | — | CN | disclosed |