Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 6/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6194507 | 0.93 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6192783 | 0.91 | HTR1A (0.48) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6195360 | 0.90 | HTR1A (0.41) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6191934 | 0.89 | MEN1 (0.43) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6211824 | 0.88 | DRD4 (0.49) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL7052092 | 0.88 | HTR1A (0.41) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6192684 | 0.87 | TSHR (0.47) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6195130 | 0.86 | POLB (0.44) | ADRA1DADRA1AADRA1BHTR1ADRD3 | |
| SCHEMBL6194300 | 0.86 | HTR1A (0.48) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6195181 | 0.85 | TSHR (0.47) | ADRA1DADRA1AADRA1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432701-B1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS OF THE URINARY TRACT | RECORDATI IRELAND LTD (IE) | 2005-12-21 | — | — | EP | claimed |
| EP-1432701-B1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS OF THE URINARY TRACT | RECORDATI IRELAND LTD (IE) | 2005-12-21 | — | — | EP | disclosed |