SCHEMBL6191925

SCHEMBL6191925

NCC1CN(c2ccc3c(c2)CCC(=O)CC3)C(=O)O1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.55
HTR6 P50406 6/20 0.46
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
GRM2 Q14416 3/20 0.41
CALML3 P27482 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9447636 0.91 F10 (0.53) F10HTR6MAOAMAOBGRM2
SCHEMBL9447681 0.91 F10 (0.53) F10HTR6MAOAMAOBGRM2
SCHEMBL6192208 0.87 MAOA (0.57) F10HTR6MAOAMAOBGRM2
SCHEMBL6194694 0.85 F10 (0.48) F10HTR6MAOAMAOBGRM2
SCHEMBL6212123 0.85 F10 (0.48) F10HTR6MAOAMAOBGRM2
SCHEMBL2183807 0.84 F10 (0.50) F10HTR6MAOAMAOBGRM2
SCHEMBL2183799 0.84 F10 (0.50) F10HTR6MAOAMAOBGRM2
SCHEMBL6528456 0.82 F10 (0.50) F10MAOAMAOBGRM2CALML3
SCHEMBL6528455 0.82 F10 (0.50) F10MAOAMAOBGRM2CALML3
SCHEMBL9635182 0.81 GRM2 (0.46) F10HTR6GRM2CALML3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1594494-A1 OXAZOLIDINONE DERIVATIVES N-SUBSTITUTED BY A BICYCLIC RING, FOR USE AS ANTIBACTERIAL AGENTS Warner-Lambert Company LLC (US) 2005-11-16 EP disclosed
US-20040224939-A1 Antibacterial agents CHUPAK LOUIS S (US) 2004-11-11 US disclosed
WO-2004069244-A1 OXAZOLIDINONE DERIVATIVES N-SUBSTITUTED BY A BICYCLIC RING, FOR USE AS ANTIBACTERIAL AGENTS WARNER-LAMBERT COMPANY LLC (US) 2004-08-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040224939-A1 Antibacterial agents MRPL21, RPN2, FBL F10 2894/4885HTR6 3773/4885MAOA 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.