Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6195068 | 0.88 | PRKCQ (0.32) | PRKCQPRKCDPRKCA | |
| SCHEMBL6193609 | 0.87 | CHRNB4 (0.40) | SLC6A2SLC6A4CYP1A2CYP2C19 | |
| SCHEMBL5997687 | 0.70 | DRD2 (0.44) | SLC6A3 | |
| SCHEMBL6192015 | 0.69 | PRKCQ (0.30) | PRKCQPRKCD | |
| SCHEMBL6192472 | 0.69 | ACSL1 (0.43) | HPGD | |
| SCHEMBL5245519 | 0.69 | LTA4H (0.54) | CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL5463927 | 0.69 | LTA4H (0.54) | CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6028968 | 0.67 | CYP3A4 (0.38) | CYP3A4 | |
| SCHEMBL4866968 | 0.66 | MEN1 (0.50) | MLNR | |
| SCHEMBL6185597 | 0.65 | HRH3 (0.39) | HPGDMLNRPKMSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583751-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF CARDIOVASCULAR DISEASES | CV THERAPEUTICS, INC. (US) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004069818-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF CARDIOVASCULAR DISEASES | CV THERAPEUTICS INC. (US) | 2004-08-19 | — | — | WO | disclosed |