Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 5/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TACR2 | P21452 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6192090 | 1.00 | GHSR (0.50) | GHSROPRM1ACESMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL6162755 | 0.99 | GHSR (0.49) | GHSROPRM1ACESMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL6161929 | 0.99 | GHSR (0.49) | GHSROPRM1ACESMN1; SMN2MAPK1 | |
| SCHEMBL6162240 | 0.89 | GHSR (0.49) | GHSROPRM1ACEERAP2PLAU | |
| SCHEMBL6162248 | 0.89 | GHSR (0.49) | GHSROPRM1ACEERAP2PLAU | |
| Hydrochloric Acid SCHEMBL6162586 | 0.89 | GHSR (0.49) | GHSROPRM1ACEERAP2PLAU | |
| Hydrochloric Acid SCHEMBL6162592 | 0.89 | GHSR (0.49) | GHSROPRM1ACEERAP2PLAU | |
| SCHEMBL6164867 | 0.84 | OPRM1 (0.47) | GHSROPRM1ACETACR2ERAP2 | |
| SCHEMBL6160679 | 0.84 | OPRM1 (0.47) | GHSROPRM1ACETACR2ERAP2 | |
| SCHEMBL6192085 | 0.80 | GHSR (0.47) | GHSROPRM1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | claimed |