Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355824 | 0.78 | HTT (0.57) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL16082212 | 0.78 | HTT (0.57) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL355825 | 0.78 | HTT (0.57) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL1699503 | 0.76 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2METAP1ACHECYP19A1 | |
| SCHEMBL31619577 | 0.76 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2METAP1ACHECYP19A1 | |
| SCHEMBL1809661 | 0.75 | MAPT (0.55) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL1806126 | 0.75 | MAPT (0.55) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL11971460 | 0.75 | MAPT (0.55) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL16233623 | 0.75 | DRD2 (0.56) | ACHECYP19A1HTR2CDRD2DRD3 | |
| SCHEMBL13799409 | 0.75 | DRD2 (0.56) | ACHECYP19A1HTR2CDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439841-A4 | ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | MERCK & CO INC (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1439841-A2 | ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Merck & Co., Inc. (US) | 2004-07-28 | — | — | EP | disclosed |
| WO-2003034987-A2 | ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | MERCK & CO., INC. (US) | 2003-05-01 | — | — | WO | disclosed |