Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4924456 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL2294091 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL668569 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL852092 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL8876177 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL2761848 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL6620970 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL3277379 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL2283898 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL7168696 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3705472-B1 | METHOD FOR PRODUCING PROSTAGLANDIN DERIVATIVE | AGC INC (JP) | 2023-06-21 | — | — | EP | disclosed |
| CN-110938003-B | Preparation method of fingolimod hydrochloride | 新发药业有限公司 | 2022-11-22 | — | — | CN | disclosed |
| US-11377413-B2 | Method for producing prostaglandin derivative | AGC Inc. (JP) | 2022-07-05 | — | — | US | disclosed |
| CN-111263750-B | Process for producing prostaglandin derivative | ＡＧＣ株式会社 | 2022-02-25 | — | — | CN | disclosed |
| EP-3705472-A1 | METHOD FOR PRODUCING PROSTAGLANDIN DERIVATIVE | AGC Inc. (JP) | 2020-09-09 | — | — | EP | disclosed |
| US-20200239397-A1 | METHOD FOR PRODUCING PROSTAGLANDIN DERIVATIVE | AGC Inc. (JP) | 2020-07-30 | — | — | US | disclosed |
| CN-111263750-A | Process for producing prostaglandin derivative | ＡＧＣ株式会社 | 2020-06-09 | — | — | CN | disclosed |
| CN-110938003-A | Preparation method of fingolimod hydrochloride | 新发药业有限公司 | 2020-03-31 | — | — | CN | disclosed |
| CN-102746294-B | (S, S)-2,8-preparation method of diazabicyclo [4.3.0] nonane | GUO FENG (CN) | 2016-04-06 | — | — | CN | disclosed |
| EP-1432701-B1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS OF THE URINARY TRACT | RECORDATI IRELAND LTD (IE) | 2005-12-21 | — | — | EP | disclosed |
| EP-1140854-A2 | METHODS FOR THE SYNTHESIS OF ALPHA-HYDROXY-BETA-AMINO ACID AND AMIDE DERIVATIVES | CORVAS INTERNATIONAL, INC. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035868-A2 | METHODS FOR THE SYNTHESIS OF ALPHA-HYDROXY-BETA-AMINO ACID AND AMIDE DERIVATIVES | CORVAS INTERNATIONAL, INC. (US) | 2000-06-22 | — | — | WO | disclosed |
| US-5389647-A | A prodrugs as hypotensive agents, treating congestive heart failure, urogenital disorders, vision defects | ABBOTT LABORATORIES (US) | 1995-02-14 | — | — | US | disclosed |
| US-5244910-A | Treating hypertension, congestive heart failure | ABBOTT LABORATORIES (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0550025-A1 | Azaspiroheptanes and octanes and processes for their production | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |
| EP-0543936-A4 | RENIN INHIBITORS | — | 1993-06-30 | — | — | EP | disclosed |
| EP-0543936-A1 | RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003429-A1 | RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1992-03-05 | — | — | WO | disclosed |
| US-4839353-A | Anti-ulcer substituted pyridine derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-06-13 | — | — | US | disclosed |
| EP-0264883-A2 | Substituted pyridine derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-04-27 | — | — | EP | disclosed |