Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7168693 | 1.00 | — | — | |
| Water SCHEMBL3391027 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL2294091 | 0.87 | — | — | |
| SCHEMBL28709874 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL6213694 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL2283898 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL8876177 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL6196264 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL6620970 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL6213692 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3705472-B1 | METHOD FOR PRODUCING PROSTAGLANDIN DERIVATIVE | AGC INC (JP) | 2023-06-21 | — | — | EP | disclosed |
| WO-2023073574-A1 | PROCESS FOR THE PREPARATION OF PIPERIDINE CARBOXAMIDES SALT FORMS AND THEREOF | CELLIX BIO PRIVATE LIMITED (IN) | 2023-05-04 | — | — | WO | disclosed |
| US-11377413-B2 | Method for producing prostaglandin derivative | AGC Inc. (JP) | 2022-07-05 | — | — | US | disclosed |
| CN-111263750-B | Process for producing prostaglandin derivative | ＡＧＣ株式会社 | 2022-02-25 | — | — | CN | disclosed |
| EP-3705472-A1 | METHOD FOR PRODUCING PROSTAGLANDIN DERIVATIVE | AGC Inc. (JP) | 2020-09-09 | — | — | EP | disclosed |
| US-20200239397-A1 | METHOD FOR PRODUCING PROSTAGLANDIN DERIVATIVE | AGC Inc. (JP) | 2020-07-30 | — | — | US | disclosed |
| CN-111263750-A | Process for producing prostaglandin derivative | ＡＧＣ株式会社 | 2020-06-09 | — | — | CN | disclosed |
| CN-104788485-B | The method for preparing antiviral agent | 百时美－施贵宝爱尔兰控股公司 | 2017-10-03 | — | — | CN | disclosed |
| EP-1644384-B1 | PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF ENTECAVIR | BRISTOL MYERS SQUIBB CO (US) | 2012-10-31 | — | — | EP | disclosed |
| EP-2433941-A1 | Process for isolating the antiviral agent [1S-(1alpha, 3alpha, 4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one | Bristol-Myers Squibb Company (US) | 2012-03-28 | — | — | EP | disclosed |
| US-20040192912-A1 | Process for preparing the antiviral agent [1S-(1alpha,3 alpha,4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one | BRISTOL-MYERS SQUIBB COMPANY | 2004-09-30 | — | — | US | disclosed |
| WO-2004052310-A2 | PROCESS AND INTERMEDIATES FOR SYNTHESIS ENTECAVIR | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |
| US-6191279-B1 | 8-HYDROXY-2,2,6,7-TETRAMETHYL-7,8,9,10-TETRAHYDRO-2H,6H-DIPYRANO (2,3-F:2,3-H)QUINOLIN-10-ONE, FOR EXAMPLE; SCREENING FOR ANTI-HIV ACTIVITY; BETTER SOLUBILITY, METABOLIC STABILITY | COUNCIL OF SCIENCE & INDUSTRIAL RESEARCH | 2001-02-20 | — | — | US | disclosed |
| US-5420310-A | Anticoagulants, antiulcer, antiatherosclerosis agents formed in multistage reaction | TORAY INDUSTRIES, INC. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0381959-B1 | Cyclohexaneacetamide derivatives | HOFFMANN LA ROCHE (CH) | 1995-05-03 | — | — | EP | disclosed |
| EP-0463162-B1 | PREPARATION OF 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES | TORAY INDUSTRIES (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5202447-A | Stereospecific | TORAY INDUSTRIES, INC. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0463162-A1 | PREPARATION OF 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1992-01-02 | — | — | EP | disclosed |
| US-5015653-A | Posess Cognitive Enhancement And Antiamnestic Activity | HOFFMANN-LA ROCHE INC. (US) | 1991-05-14 | — | — | US | disclosed |
| EP-0381959-A1 | Cyclohexaneacetamide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1990-08-16 | — | — | EP | disclosed |