Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6494472 | 0.83 | SPHK1 (0.39) | CTSSCTSKTP53LMNACNR1 | |
| SCHEMBL6194742 | 0.76 | GRM2 (0.37) | CNR1CNR2GRM2GRM3NAAA | |
| SCHEMBL6196321 | 0.76 | GRM2 (0.37) | CNR1CNR2GRM2GRM3NAAA | |
| SCHEMBL6493631 | 0.76 | GRM2 (0.38) | CTSSCTSKCNR1CNR2GRM2 | |
| SCHEMBL8818712 | 0.70 | ALDH1A1 (0.36) | CYP2C9CYP2C19 | |
| SCHEMBL10582156 | 0.68 | SPHK1 (0.36) | — | |
| SCHEMBL14338696 | 0.68 | SPHK1 (0.42) | — | |
| SCHEMBL14350826 | 0.68 | SPHK1 (0.42) | — | |
| SCHEMBL6924329 | 0.68 | SPHK1 (0.42) | — | |
| SCHEMBL7686350 | 0.67 | SPHK1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446402-B1 | 2-AMINO-4-HETEROARYLETHYL THIAZOLINE DERIVATIVES AND THEIR USE AN INHIBITORS OF INDUCIBLE NO-SYNTHASE | AVENTIS PHARMA SA (FR) | 2005-11-02 | — | — | EP | claimed |