Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA4 | P22748 | 4/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL564865 | 0.86 | ACHE (0.52) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Ethyne SCHEMBL4043028 | 0.84 | ACHE (0.50) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL22443107 | 0.82 | TSHR (0.42) | TSHRAPOBEC3AHTTAPOBEC3GTUBB1 | |
| SCHEMBL523635 | 0.81 | TSHR (0.46) | TSHRAPOBEC3AHTTAPOBEC3GCA2 | |
| SCHEMBL12435004 | 0.78 | ACHE (0.45) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31004967 | 0.74 | ACHE (0.40) | HTTACHECYP3A4MAPTCA9 | |
| SCHEMBL670539 | 0.74 | ALDH1A1 (0.47) | HTTTUBB1MAPTLMNAHPGD | |
| SCHEMBL29254171 | 0.73 | HTR2A (0.51) | TSHRTUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL5236856 | 0.73 | TUBB1 (0.58) | TSHRAPOBEC3AHTTAPOBEC3GCA2 | |
| SCHEMBL29254183 | 0.72 | ACHE (0.33) | TSHRHTTACHECYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-B1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO MCNEIL PHARM INC (US) | 2005-02-16 | — | — | EP | claimed |
| WO-2011092128-A1 | SUBSTITUTED NAPHTHYRIDINES AND THEIR USE AS SYK KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | WO | disclosed |