Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.44 |
| ▸ | TLR4 | O00206 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287786 | 0.82 | KMT2A (0.59) | KMT2APTGES2TLR4 | |
| SCHEMBL8521457 | 0.81 | KMT2A (0.48) | KMT2APTGES2ACLYCA2CA1 | |
| SCHEMBL22315270 | 0.80 | KMT2A (0.59) | KMT2APTGES2TSHRMEN1ACLY | |
| SCHEMBL16492686 | 0.79 | KMT2A (0.55) | KMT2ATLR4TSHRMEN1ACLY | |
| SCHEMBL27182630 | 0.77 | KMT2A (0.54) | KMT2ATLR4TSHRMEN1ACLY | |
| SCHEMBL10344599 | 0.77 | ALDH1A1 (0.49) | KMT2ACA2CA1NPC1RAB9A | |
| SCHEMBL22315384 | 0.76 | MCL1 (0.54) | KMT2ATSHRMEN1ACLYCA2 | |
| SCHEMBL20290537 | 0.75 | KMT2A (0.51) | KMT2APTGES2TLR4TSHRMEN1 | |
| SCHEMBL19997238 | 0.75 | KMT2A (0.51) | KMT2ATLR4TSHRMEN1ACLY | |
| SCHEMBL22315132 | 0.73 | MEN1 (0.67) | KMT2ATSHRMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973739-B1 | N-ARYLSULFONAMIDE- AND PYRROLIDINECARBOXYLIC ACID INTERMEDIATES, AND THEIR USE FOR THE PREPARATION OF HERBICIDAL 1,3-DIOXO-1H-PYRROLO[1,2-C]IMIDAZOLE DERIVATIVES | DEGUSSA (DE) | 2005-11-02 | — | — | EP | disclosed |
| US-6664400-B2 | 1-((4-halo-3-sulfonamidophenyl)aminocarbonyl),2-carboxy -pyrrolidine intermediate of given formula | DEGUSSA AG (DE) | 2003-12-16 | — | — | US | disclosed |
| US-20020137946-A1 | N-arylsulfonamide and pyrrolidinecarboxylic acid intermediates, and their use for the preparation of herbicidal 1,3-dioxo-1h-pyrrolo[1,2-c]imidazole derivatives | DEGUSSA AG (DE) | 2002-09-26 | — | — | US | disclosed |
| US-6384234-B1 | HALOGENATION | DEGUSSA AG (DE) | 2002-05-07 | — | — | US | disclosed |
| EP-0973739-A1 | N-ARYLSULFONAMIDE- AND PYRROLIDINECARBOXYLIC ACID INTERMEDIATES, AND THEIR USE FOR THE PREPARATION OF HERBICIDAL 1,3-DIOXO-1H-PYRROLO[1,2-C]IMIDAZOLE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998037065-A1 | N-ARYLSULFONAMIDE- AND PYRROLIDINECARBOXYLIC ACID INTERMEDIATES, AND THEIR USE FOR THE PREPARATION OF HERBICIDAL 1,3-DIOXO-1H-PYRROLO[1,2-C]IMIDAZOLE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137946-A1 | N-arylsulfonamide and pyrrolidinecarboxylic acid intermediates, and their use for the preparation of herbicidal 1,3-dioxo-1h-pyrrolo[1,2-c]imidazole derivatives | CBR3, CBR1, CLIC1 | KMT2A 2863/4885PTGES2 3525/4885TLR4 2517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.