Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 6/20 | 0.35 |
| ▸ | MMP2 | P08253 | 4/20 | 0.35 |
| ▸ | MMP13 | P45452 | 5/20 | 0.35 |
| ▸ | MMP3 | P08254 | 5/20 | 0.35 |
| ▸ | MMP8 | P22894 | 3/20 | 0.35 |
| ▸ | MMP14 | P50281 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.34 |
| ▸ | MMP10 | P09238 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201196 | 0.91 | MMP9 (0.35) | MMP9MMP2MMP13MMP3MMP8 | |
| SCHEMBL6203133 | 0.90 | SMN1; SMN2 (0.38) | MMP9MMP2MMP13MMP3MMP8 | |
| SCHEMBL6734114 | 0.84 | SMN1; SMN2 (0.40) | MMP9MMP2MMP13MMP3MMP8 | |
| SCHEMBL6202138 | 0.84 | MMP9 (0.37) | MMP9MMP2MMP13MMP3MMP8 | |
| SCHEMBL5908943 | 0.82 | MMP9 (0.38) | MMP9MMP2MMP13MMP3MMP8 | |
| Hydrochloric Acid SCHEMBL6197901 | 0.81 | MMP9 (0.33) | MMP9MMP2MMP13MMP3MMP8 | |
| Hydrochloric Acid SCHEMBL6198320 | 0.80 | MMP3 (0.39) | MMP9MMP2MMP13MMP3MMP8 | |
| SCHEMBL6201542 | 0.80 | MMP9 (0.37) | MMP9MMP2MMP13MMP3MMP8 | |
| SCHEMBL5908565 | 0.78 | MMP9 (0.48) | MMP9MMP2MMP13MMP3MMP8 | |
| SCHEMBL5908721 | 0.77 | MMP9 (0.58) | MMP9MMP2MMP13MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515951-A1 | ARYLSULFONYLHYDROXAMIC ACID AND AMIDE DERIVATIVES AND THEIR USE AS PROTEASE INHIBITORS | Pharmacia Corporation (US) | 2005-03-23 | — | — | EP | disclosed |
| WO-2004000811-A1 | ARYLSULFONYLHYDROXAMIC ACID AND AMIDE DERIVATIVES AND THEIR USE AS PROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2003-12-31 | — | — | WO | disclosed |