Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CPB1 | P15086 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6193079 | 0.85 | SLC18A3 (0.40) | SLC18A3ALDH1A1MAPTKEAP1HTR2A | |
| SCHEMBL6194530 | 0.78 | HTR2C (0.44) | SLC18A3ALDH1A1HTR2APOLBHSD11B1 | |
| SCHEMBL6193429 | 0.77 | RIPK1 (0.36) | ALDH1A1MAPTKEAP1HTR2APOLB | |
| SCHEMBL6194363 | 0.76 | FASN (0.45) | SLC18A3ALDH1A1POLBKMT2A | |
| SCHEMBL6194843 | 0.76 | ALDH1A1 (0.35) | ALDH1A1MAPTKEAP1HTR2AHSD11B1 | |
| SCHEMBL6194416 | 0.75 | CNR1 (0.36) | KEAP1POLBGAANPSR1 | |
| SCHEMBL6193727 | 0.74 | MEN1 (0.40) | SMYD3POLBGAANPSR1MEN1 | |
| SCHEMBL6192678 | 0.74 | DRD3 (0.44) | SLC18A3ALDH1A1HTR2A | |
| SCHEMBL6193834 | 0.74 | GRIN2B (0.38) | SLC18A3ALDH1A1KEAP1 | |
| SCHEMBL6192829 | 0.74 | MEN1 (0.35) | SLC18A3ALDH1A1MAPTGAAHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432701-B1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS OF THE URINARY TRACT | RECORDATI IRELAND LTD (IE) | 2005-12-21 | — | — | EP | claimed |