Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202868 | 0.99 | NR3C1 (0.34) | NR3C1MEN1KMT2AKDM4EGAA | |
| SCHEMBL6197621 | 0.94 | NR3C1 (0.34) | NR3C1MEN1KMT2AKDM4EGAA | |
| SCHEMBL6200160 | 0.90 | NR3C1 (0.33) | NR3C1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6199997 | 0.89 | NR3C1 (0.33) | NR3C1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6198743 | 0.86 | EGLN1 (0.35) | NR3C1MEN1KMT2AKDM4EGAA | |
| SCHEMBL6199424 | 0.86 | EGLN1 (0.35) | NR3C1MEN1KMT2AKDM4EGAA | |
| SCHEMBL6682523 | 0.85 | EGLN1 (0.38) | NR3C1KDM4ELMNASMN1; SMN2HPGD | |
| SCHEMBL6199988 | 0.83 | LMNA (0.32) | NR3C1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6199416 | 0.81 | EGLN1 (0.34) | NR3C1MEN1KMT2ACCR1EGLN1 | |
| SCHEMBL6669431 | 0.81 | LMNA (0.33) | NR3C1MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |