Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702501 | 0.90 | PTPN1 (0.57) | ALDH1A1KDM4EMAPTPTPN1SMN1; SMN2 | |
| SCHEMBL18066376 | 0.89 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAMRGPRX4MAPT | |
| SCHEMBL27539388 | 0.88 | KDM4E (0.57) | ALDH1A1KDM4ELMNAMRGPRX4MAPT | |
| SCHEMBL4627636 | 0.88 | NPC1 (0.60) | KDM4EMRGPRX4NPC1HPGDRAB9A | |
| SCHEMBL6615190 | 0.87 | KDM4E (0.54) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL4363943 | 0.85 | MAOB (0.57) | ALDH1A1PTPN1NPC1HPGDRAB9A | |
| SCHEMBL8000403 | 0.85 | MAOB (0.57) | ALDH1A1PTPN1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15094958 | 0.84 | KDM4E (0.53) | ALDH1A1KDM4ELMNAMRGPRX4MAPT | |
| SCHEMBL18985160 | 0.83 | FFAR4 (0.59) | ALDH1A1KDM4EMRGPRX4MAPTPTPN1 | |
| SCHEMBL1315571 | 0.83 | KDM4E (0.68) | ALDH1A1KDM4EMAPTHSD17B10PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513817-A1 | 1, 2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Pharmaceutical Company Limited (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003099793-A9 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL (JP) | 2005-02-10 | — | — | WO | disclosed |
| WO-2003099793-A1 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-12-04 | — | — | WO | disclosed |