Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363943 | 0.94 | MAOB (0.57) | MAOBPTPN1NR4A2ALDH1A1SRD5A2 | |
| SCHEMBL6702501 | 0.94 | PTPN1 (0.57) | MAOBPTPN1NR4A2ALDH1A1SRD5A2 | |
| SCHEMBL18066376 | 0.93 | ALDH1A1 (0.54) | MAOBPTPN1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL19712578 | 0.92 | MAOB (0.55) | MAOBPTPN1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6199290 | 0.92 | MTNR1A (0.57) | MAOBPTPN1HTTSMN1; SMN2SMPD1 | |
| SCHEMBL18066374 | 0.91 | PTPN1 (0.51) | MAOBPTPN1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL18066371 | 0.91 | PTPN1 (0.51) | MAOBPTPN1ALDH1A1L3MBTL1ALOX5 | |
| SCHEMBL6195352 | 0.89 | MAOB (0.55) | MAOBPTPN1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL27934106 | 0.88 | MAOB (0.49) | MAOBPTPN1ALDH1A1SRD5A2HTT | |
| SCHEMBL4847906 | 0.87 | PTPN1 (0.63) | MAOBPTPN1NR4A2ALDH1A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288096-B1 | ANTIDIABETIC AGENTS, HYPOTENSIVE AGENTS, AND ANTICHOLESTEROL AGENTS | ASTRAZENECA AB (SE) | 2001-09-11 | — | — | US | disclosed |
| US-4990511-A | Amide compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0353753-A1 | Amide compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-02-07 | — | — | EP | disclosed |
| EP-0311517-A2 | Amide compound having glutamate receptor inhibiting activity | Takeda Chemical Industries, Ltd. (JP) | 1989-04-12 | — | — | EP | disclosed |