Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | OGA | O60502 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RBP4 | P02753 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SORD | Q00796 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354208 | 0.82 | ADRB1 (0.78) | ADRB1OGAPKMKMT2ASLC6A7 | |
| SCHEMBL13677029 | 0.80 | OGA (0.65) | ADRB1OGAPKMKMT2ASLC6A7 | |
| SCHEMBL28070992 | 0.76 | ADRB1 (0.73) | ADRB1OGAPKMKMT2ASLC6A7 | |
| SCHEMBL25809682 | 0.75 | OGA (0.60) | ADRB1OGAPKMKMT2ASLC6A7 | |
| SCHEMBL12969642 | 0.75 | ADRB1 (0.68) | ADRB1OGAPKMKMT2ASLC6A7 | |
| SCHEMBL13286847 | 0.74 | ADRB1 (0.71) | ADRB1OGAPKMKMT2ASLC6A7 | |
| SCHEMBL3556451 | 0.74 | ADRB1 (0.71) | ADRB1OGAPKMKMT2ASLC6A7 | |
| SCHEMBL1999765 | 0.73 | ADRB1 (0.69) | ADRB1OGAPKMKMT2ASLC6A7 | |
| SCHEMBL5232026 | 0.73 | SLC6A7 (0.68) | ADRB1OGAPKMKMT2ASLC6A7 | |
| SCHEMBL230177 | 0.72 | ADRB1 (1.00) | ADRB1OGAPKMKMT2ASLC6A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525199-A1 | SUBSTITUTED THIENYL-HYDROXAMIC ACIDS AS HISTONE DEACETYLASE INHIBITORS | Argenta Discovery Limited (GB) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004013130-A1 | SUBSTITUTED THIENYL-HYDROXAMIC ACIDS AS HISTONE DEACETYLASE INHIBITORS | ARGENTA DISCOVERY LIMITED (GB) | 2004-02-12 | — | — | WO | disclosed |