SCHEMBL6199757

SCHEMBL6199757

C=C/C=C/C/C=C/CC/C=C/CC/C=C/CC/C=C/CC/C=C/CC/C=C/CC/C=C/CC/C=C/C

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.31
ALDH1A1 P00352 2/20 0.30
MAPT P10636 2/20 0.30
FFAR1 O14842 1/20 0.30
CYP19A1 P11511 1/20 0.30
RXRA P19793 1/20 0.30
PPARG P37231 1/20 0.30
OXER1 Q8TDS5 1/20 0.30
F13A1 P00488 1/20 0.30
THRB P10828 1/20 0.30
PTGS1 P23219 1/20 0.30
FASN P49327 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4929461 1.00 PPARA (0.31) PPARAALDH1A1MAPTFFAR1CYP19A1
SCHEMBL6199761 1.00 PPARA (0.31) PPARAALDH1A1MAPTFFAR1CYP19A1
SCHEMBL4929453 1.00 PPARA (0.31) PPARAALDH1A1MAPTFFAR1CYP19A1
SCHEMBL6202636 0.92 ALDH1A1 (0.38) PPARAALDH1A1MAPTFFAR1CYP19A1
SCHEMBL6202638 0.92 ALDH1A1 (0.38) PPARAALDH1A1MAPTFFAR1CYP19A1
SCHEMBL16103147 0.88 ALOX12 (0.33) PPARAALDH1A1MAPTFFAR1CYP19A1
SCHEMBL16103148 0.88 ALOX12 (0.33) PPARAALDH1A1MAPTFFAR1CYP19A1
SCHEMBL28427560 0.87
SCHEMBL22611958 0.87 LSS (0.33) PPARAPPARG
SCHEMBL22611959 0.87 LSS (0.33) PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1268457-A4 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORP (US) 2005-07-20 EP claimed
JP-2003529643-A 2003-10-07 JP claimed
EP-1268457-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2003-01-02 EP claimed
WO-2001074798-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2001-10-11 WO claimed