Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 3/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201118 | 0.88 | EGLN1 (0.44) | LMNAEGLN1HPGD | |
| SCHEMBL6204166 | 0.85 | EGLN1 (0.43) | LMNAEGLN1HPGD | |
| SCHEMBL6199810 | 0.84 | LMNA (0.46) | P2RX1TMPRSS4LMNACNR2EGLN1 | |
| SCHEMBL6201589 | 0.84 | EGLN1 (0.42) | LMNAEGLN1HPGD | |
| SCHEMBL6203808 | 0.84 | EGLN1 (0.49) | LMNACNR2EGLN1HPGD | |
| SCHEMBL6201955 | 0.84 | EGLN1 (0.42) | EGLN1HPGD | |
| SCHEMBL6201571 | 0.84 | SMN1; SMN2 (0.45) | LMNACNR2EGLN1MAPT | |
| SCHEMBL6200398 | 0.81 | EGLN1 (0.44) | LMNAEGLN1HPGD | |
| SCHEMBL6201600 | 0.79 | EGLN1 (0.47) | LMNACNR2EGLN1HPGD | |
| SCHEMBL6201231 | 0.79 | EGLN1 (0.44) | LMNACNR2EGLN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |