Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200539 | 1.00 | HTR6 (0.51) | HTR6CHRM2CHRM1HTR2CHTR2A | |
| SCHEMBL6200709 | 1.00 | HTR6 (0.51) | HTR6CHRM2CHRM1HTR2CHTR2A | |
| SCHEMBL6220778 | 1.00 | HTR6 (0.51) | HTR6CHRM2CHRM1HTR2CHTR2A | |
| SCHEMBL6220570 | 1.00 | HTR6 (0.51) | HTR6CHRM2CHRM1HTR2CHTR2A | |
| SCHEMBL6201915 | 1.00 | HTR6 (0.51) | HTR6CHRM2CHRM1HTR2CHTR2A | |
| SCHEMBL6201184 | 1.00 | HTR6 (0.51) | HTR6CHRM2CHRM1HTR2CHTR2A | |
| SCHEMBL6217043 | 0.91 | HTR2A (0.42) | HTR6HTR2CHTR2ALMNA | |
| SCHEMBL6220462 | 0.91 | HTR2A (0.42) | HTR6HTR2CHTR2ALMNA | |
| SCHEMBL6197664 | 0.91 | HTR2A (0.42) | HTR6HTR2CHTR2ALMNA | |
| SCHEMBL6198240 | 0.91 | HTR2A (0.42) | HTR6HTR2CHTR2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351961-B1 | SUBSTITUTED INDOLINES AS 5-HT RECEPTOR LIGANDS | PHARMACIA & UPJOHN CO LLC (US) | 2005-07-27 | — | — | EP | claimed |