Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 11/20 | 0.67 |
| ▸ | AGXT | P21549 | 8/20 | 0.64 |
| ▸ | LTA4H | P09960 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | BAX | Q07812 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7236178 | 0.98 | AGXT (0.68) | IDO1AGXTLTA4HTSHRNR1H2 | |
| SCHEMBL8994543 | 0.82 | TSHR (0.64) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL1715197 | 0.82 | IDO1 (0.65) | IDO1AGXTCYP3A4 | |
| SCHEMBL7948 | 0.81 | — | — | |
| SCHEMBL20469087 | 0.81 | IDO1 (1.00) | IDO1AGXTTSHRCYP3A4 | |
| SCHEMBL12311482 | 0.81 | IDO1 (0.71) | IDO1AGXTLTA4HMAOA | |
| Hydrochloric Acid SCHEMBL9716600 | 0.80 | IDO1 (0.66) | IDO1AGXTLTA4HCYP3A4 | |
| SCHEMBL891493 | 0.80 | FFAR1 (0.69) | LTA4HMAOA | |
| Bromide SCHEMBL8996427 | 0.79 | IDO1 (0.94) | IDO1AGXTTSHRCYP3A4 | |
| SCHEMBL8863651 | 0.79 | IDO1 (0.94) | IDO1AGXTTSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312200-B2 | 9-ketospinosyn derivatives | BAYER CROPSCIENCE AG (DE) | 2007-12-25 | — | — | US | disclosed |
| US-7312200-B2 | 9-ketospinosyn derivatives | BAYER CROPSCIENCE AG (DE) | 2007-12-25 | — | — | US | disclosed |
| EP-1266887-B1 | Indenoindoline derivatives, their process of preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-08-17 | — | — | EP | disclosed |
| CN-1390834-A | Indenoindolone compounds, their preparation and medicinal compositions containing them | SEUVILE LAB (FR) | 2003-01-15 | — | — | CN | disclosed |
| EP-1266887-A2 | Indenoindoline derivatives, their process of preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2002-12-18 | — | — | EP | disclosed |
| EP-0015456-B1 | OMEGA-HALOGENO-ACETOPHENONE OXIME ETHERS, PREPARATION THEREOF AND THEIR USE AS INTERMEDIATES IN THE PREPARATION OF OMEGA-AZOLYL-ACETOPHENONE OXIME ETHERS | BAYER AG (DE) | 1981-12-02 | — | — | EP | disclosed |
| US-4293715-A | FUNGICIDES, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | disclosed |