Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | LTA4H | P09960 | 5/20 | 0.61 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | BAX | Q07812 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylether SCHEMBL27567755 | 0.93 | TSHR (0.75) | TSHRLTA4HNR1H2BAXNAAA | |
| SCHEMBL22199637 | 0.90 | HTT (0.53) | TSHRLTA4HNR1H2BAXNAAA | |
| SCHEMBL6002344 | 0.87 | LTA4H (0.53) | TSHRLTA4HNR1H2BAXNAAA | |
| SCHEMBL10944998 | 0.84 | LTA4H (0.50) | TSHRLTA4HNR1H2BAXNAAA | |
| SCHEMBL891493 | 0.84 | FFAR1 (0.69) | LTA4HFFAR1FFAR4MAOAPPARG | |
| SCHEMBL17758006 | 0.82 | NAAA (0.50) | TSHRLTA4HNR1H2BAXNAAA | |
| SCHEMBL2088939 | 0.82 | LTA4H (0.57) | TSHRLTA4HNR1H2BAXNAAA | |
| SCHEMBL6200077 | 0.82 | IDO1 (0.67) | TSHRLTA4HNR1H2BAXMAOA | |
| SCHEMBL2088942 | 0.82 | LTA4H (0.58) | TSHRLTA4HNR1H2BAXNAAA | |
| SCHEMBL9795394 | 0.82 | TSHR (0.94) | TSHRLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501912-B1 | Methyldioxolane | CIBA GEIGY AG (CH) | 1996-08-14 | — | — | EP | disclosed |
| US-5478958-A | Stereoselective acetalization catalyst | CIBA-GEIGY CORPORATION (US) | 1995-12-26 | — | — | US | disclosed |
| US-5384416-A | Stereospecific insecticides | CIBA-GEIGY CORPORATION (US) | 1995-01-24 | — | — | US | disclosed |
| US-5280041-A | Such as 4-((4-phenoxyphenoxy)methyl)dioxolan | CIBA-GEIGY CORPORATION (US) | 1994-01-18 | — | — | US | disclosed |
| EP-0501912-A1 | Methyldioxolane | CIBA-GEIGY AG (CH) | 1992-09-02 | — | — | EP | disclosed |