SCHEMBL891493

SCHEMBL891493

c1ccc(Oc2ccc(OCc3ccc(COc4ccc(Oc5ccccc5)cc4)cc3)cc2)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.69
FFAR4 Q5NUL3 2/20 0.69
APP P05067 2/20 0.67
LMNA P02545 1/20 0.63
CYP1A2 P05177 1/20 0.63
PTGS1 P23219 1/20 0.63
SLC6A2 P23975 1/20 0.63
CYP2C19 P33261 1/20 0.63
PTGS2 P35354 1/20 0.63
SLC6A3 Q01959 1/20 0.63
HIF1A Q16665 1/20 0.63
HDAC6 Q9UBN7 1/20 0.63
PPARG P37231 1/20 0.63
MAOB P27338 3/20 0.62
BCHE P06276 1/20 0.62
GAA P10253 1/20 0.61
MAPT P10636 1/20 0.61
MAOA P21397 1/20 0.61
RAB9A P51151 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11849334 0.95 LMNA (0.69) FFAR1FFAR4APPLMNACYP1A2
SCHEMBL5538712 0.93 LMNA (0.72) FFAR1FFAR4APPLMNACYP1A2
SCHEMBL28398918 0.92 LMNA (0.78) FFAR1FFAR4APPLMNACYP1A2
SCHEMBL10609652 0.91 LMNA (0.75) FFAR1FFAR4APPLMNACYP1A2
SCHEMBL850999 0.91 APP (0.78) FFAR1APPLMNACYP1A2PTGS1
SCHEMBL11853239 0.90 APP (0.62) FFAR1FFAR4APPLMNACYP1A2
SCHEMBL11857425 0.90 MAOB (0.62) FFAR1FFAR4APPLMNACYP1A2
SCHEMBL11855314 0.90 LTA4H (0.60) FFAR1FFAR4APPLMNACYP1A2
SCHEMBL11856772 0.90 APP (0.85) FFAR1FFAR4APPPPARG
SCHEMBL11844522 0.90 LTA4H (0.67) FFAR1FFAR4APPPPARGMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722574-B2 Thermal imaging members and methods ZINK IMAGING, INC. (US) 2014-05-13 US claimed
US-20130059726-A1 THERMAL IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. 2013-03-07 US claimed
US-7807607-B2 Color-forming compounds and use thereof in imaging members and methods ZINK IMAGING, INC. (US) 2010-10-05 US claimed
WO-2010075544-A1 NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. (US) 2010-07-01 WO claimed
US-20090137389-A1 NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. 2009-05-28 US claimed
EP-2461984-B1 THERMALLY-INSULATING LAYERS AND DIRECT THERMAL IMAGING MEMBERS CONTAINING SAME ZINK IMAGING INC (US) 2016-05-04 EP disclosed
EP-2485900-B1 MULTICOLOUR THERMAL IMAGING MATERIAL ZINK IMAGING INC (US) 2014-05-21 EP disclosed
US-20130303670-A1 COMPOSITIONS, THERMALLY-INSULATING LAYERS, AND DIRECT THERMALLY IMAGING MEMBERS CONTAINING THE SAME ZINK IMAGING INC (US) 2013-11-14 US disclosed
US-8377844-B2 Thermally-insulating layers and direct thermal imaging members containing same ZINK IMAGING, INC. (US) 2013-02-19 US disclosed
US-8372782-B2 Imaging system ZINK IMAGING, INC. (US) 2013-02-12 US disclosed
EP-2485900-A1 MULTICOLOUR THERMAL IMAGING MATERIAL Zink Imaging, Inc. (US) 2012-08-15 EP disclosed
EP-2461984-A1 THERMALLY-INSULATING LAYERS AND DIRECT THERMAL IMAGING MEMBERS CONTAINING SAME Zink Imaging, Inc. (US) 2012-06-13 EP disclosed
US-20110098487-A1 NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. 2011-04-28 US disclosed
WO-2011044049-A1 MULTICOLOUR THERMAL IMAGING MATERIAL ZINK IMAGING, INC. (US) 2011-04-14 WO disclosed
WO-2011017184-A1 THERMALLY-INSULATING LAYERS AND DIRECT THERMAL IMAGING MEMBERS CONTAINING SAME ZINK IMAGING, INC. (US) 2011-02-10 WO disclosed
US-7807607-B2 Color-forming compounds and use thereof in imaging members and methods ZINK IMAGING, INC. (US) 2010-10-05 US disclosed
WO-2010075544-A1 NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. (US) 2010-07-01 WO disclosed
US-20100099556-A1 Imaging System ZINK IMAGING, INC. 2010-04-22 US disclosed
US-20100087316-A1 Thermally-Insulating Layers and Direct Thermal Imaging Members Containing Same ZINK HOLDINGS LLC 2010-04-08 US disclosed
US-20090137389-A1 NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. 2009-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098487-A1 NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS HCCS, RB1, CACYBP FFAR1 4119/4885FFAR4 3920/4885APP 3302/4885
US-20130059726-A1 THERMAL IMAGING MEMBERS AND METHODS HEATR1, HEATR6, HSPBP1 FFAR1 3364/4885FFAR4 3320/4885APP 3601/4885
US-20090137389-A1 NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS HCCS, RB1, CACYBP FFAR1 4119/4885FFAR4 3920/4885APP 3302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.