Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | STAMBP | O95630 | 1/20 | 0.36 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199205 | 0.89 | TUBB (0.43) | MCL1TUBBCA2CA4EGLN1 | |
| SCHEMBL6201217 | 0.88 | MCL1 (0.47) | MCL1TUBBEGLN1LMNAALDH1A1 | |
| SCHEMBL6201979 | 0.88 | MCL1 (0.52) | MCL1TUBBEGLN1LMNAALDH1A1 | |
| SCHEMBL6199567 | 0.86 | MCL1 (0.44) | MCL1TUBBCA2EGLN1LMNA | |
| SCHEMBL6199253 | 0.84 | MCL1 (0.44) | MCL1TUBBEGLN1LMNAALDH1A1 | |
| SCHEMBL6201109 | 0.84 | MCL1 (0.47) | MCL1TUBBEGLN1LMNAALDH1A1 | |
| SCHEMBL6197449 | 0.84 | MCL1 (0.48) | MCL1TUBBEGLN1LMNAALDH1A1 | |
| SCHEMBL6198581 | 0.84 | MCL1 (0.48) | MCL1TUBBEGLN1LMNAALDH1A1 | |
| SCHEMBL6200211 | 0.84 | MCL1 (0.48) | MCL1TUBBCA2EGLN1LMNA | |
| SCHEMBL6200333 | 0.83 | MCL1 (0.48) | MCL1TUBBEGLN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |