Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201594 | 0.95 | KMT2A (0.46) | TP53RXFP1KCNH2MEN1KMT2A | |
| SCHEMBL6199188 | 0.93 | SLC2A1 (0.41) | TP53EPHX2NAMPT | |
| SCHEMBL6200143 | 0.88 | KMT2A (0.45) | TP53EPHX2RXFP1KCNH2MEN1 | |
| SCHEMBL6202413 | 0.86 | MCL1 (0.43) | TP53LMNAPOLA1CYP2C19ALDH1A1 | |
| SCHEMBL6195950 | 0.86 | LMNA (0.53) | TP53RXFP1MEN1KMT2ALMNA | |
| SCHEMBL6199074 | 0.85 | MCL1 (0.44) | TP53LMNANPSR1POLA1CYP2C19 | |
| SCHEMBL6199253 | 0.85 | MCL1 (0.44) | TP53MEN1KMT2ALMNANPSR1 | |
| SCHEMBL6201656 | 0.85 | MCL1 (0.44) | TP53MEN1KMT2ALMNANPSR1 | |
| SCHEMBL6201979 | 0.85 | MCL1 (0.52) | TP53MEN1KMT2ALMNAPOLA1 | |
| SCHEMBL6204261 | 0.84 | TP53 (0.45) | TP53EPHX2RXFP1KCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |