Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200360 | 0.95 | TP53 (0.43) | KMT2ALMNANPSR1TP53POLA1 | |
| SCHEMBL6199188 | 0.89 | SLC2A1 (0.41) | TP53 | |
| SCHEMBL6197524 | 0.88 | KMT2A (0.50) | KMT2ALMNANPSR1POLA1ALDH1A1 | |
| SCHEMBL6201234 | 0.85 | MCL1 (0.42) | LMNAPOLA1ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL6202413 | 0.85 | MCL1 (0.43) | LMNATP53POLA1ALDH1A1CYP3A4 | |
| SCHEMBL6202657 | 0.84 | LMNA (0.42) | KMT2ALMNATP53ALDH1A1MEN1 | |
| SCHEMBL6195950 | 0.84 | LMNA (0.53) | KMT2ALMNATP53ALDH1A1RXFP1 | |
| SCHEMBL6199253 | 0.84 | MCL1 (0.44) | KMT2ALMNANPSR1TP53POLA1 | |
| SCHEMBL6201656 | 0.84 | MCL1 (0.44) | KMT2ALMNANPSR1TP53MEN1 | |
| SCHEMBL6199074 | 0.84 | MCL1 (0.44) | LMNANPSR1TP53POLA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |