Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200373 | 0.82 | CNR2 (0.47) | CNR2LMNAPOLBEGLN1ALDH1A1 | |
| SCHEMBL6200491 | 0.81 | MAPK1 (0.46) | CNR2LMNAEGLN1ALDH1A1RXFP1 | |
| SCHEMBL6200034 | 0.80 | TP53 (0.46) | CNR2LMNAEGLN1ALDH1A1RXFP1 | |
| SCHEMBL6196446 | 0.76 | LMNA (0.51) | CNR2LMNAPOLBEGLN1MAPT | |
| SCHEMBL6198854 | 0.75 | EGLN1 (0.54) | CNR2LMNAEGLN1ALDH1A1MEN1 | |
| SCHEMBL6198524 | 0.75 | EGLN1 (0.51) | CNR2LMNAEGLN1ALDH1A1NR3C1 | |
| SCHEMBL6198610 | 0.75 | EGLN1 (0.56) | CNR2LMNAEGLN1ALDH1A1MEN1 | |
| SCHEMBL6198755 | 0.75 | POLA1 (0.57) | CNR2LMNAEGLN1ALDH1A1MEN1 | |
| SCHEMBL6202822 | 0.75 | EGLN1 (0.51) | CNR2LMNAPOLBEGLN1ALDH1A1 | |
| SCHEMBL6198915 | 0.75 | EGLN1 (0.51) | CNR2LMNAEGLN1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |