Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 10/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 10/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737133 | 0.98 | TBXAS1 (0.37) | TBXAS1CYP4F2CYP4A11CYP2C19CPB2 | |
| SCHEMBL6273845 | 0.89 | TBXAS1 (0.42) | TBXAS1CYP4F2CYP4A11CYP2C19CPB2 | |
| SCHEMBL6267731 | 0.89 | CYP2C19 (0.47) | TBXAS1CYP4F2CYP4A11CYP2C19CPB2 | |
| SCHEMBL797992 | 0.89 | TBXAS1 (0.45) | TBXAS1CYP4F2CYP4A11CYP2C19CPB2 | |
| SCHEMBL798200 | 0.89 | TBXAS1 (0.45) | TBXAS1CYP4F2CYP4A11CYP2C19CPB2 | |
| SCHEMBL798344 | 0.89 | TBXAS1 (0.45) | TBXAS1CYP4F2CYP4A11CYP2C19CPB2 | |
| SCHEMBL798204 | 0.89 | TBXAS1 (0.45) | TBXAS1CYP4F2CYP4A11CYP2C19CPB2 | |
| SCHEMBL10257161 | 0.82 | CYP4F2 (0.53) | TBXAS1CYP4F2CYP4A11CYP2C19CPB2 | |
| SCHEMBL17099452 | 0.82 | CYP4F2 (0.53) | TBXAS1CYP4F2CYP4A11CYP2C19CPB2 | |
| SCHEMBL9182194 | 0.79 | TBXAS1 (0.54) | TBXAS1CYP4F2CYP4A11CYP2C19CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230046065-A1 | MERGING C(sp3)-H ACTIVATION WITH DNA-ENCODING | THE SCRIPPS RESEARCH INSTITUTE | 2023-02-16 | — | — | US | disclosed |
| CN-112312902-B | Pd (II) -catalyzed enantioselective C-H arylation of free carboxylic acids | 斯克里普斯研究学院 | 2022-02-18 | — | — | CN | disclosed |
| US-11021427-B2 | Pd(II)-catalyzed enantioselective C—H arylation of free carboxylic acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-06-01 | — | — | US | disclosed |
| US-11021427-B2 | Pd(II)-catalyzed enantioselective C—H arylation of free carboxylic acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-06-01 | — | — | US | disclosed |
| US-20210087131-A1 | PD(II)-CATALYZED ENANTIOSELECTIVE C-H ARYLATION OF FREE CARBOXYLIC ACIDS | THE SCRIPPS RESEARCH INSTITUTE | 2021-03-25 | — | — | US | disclosed |
| US-20210087131-A1 | PD(II)-CATALYZED ENANTIOSELECTIVE C-H ARYLATION OF FREE CARBOXYLIC ACIDS | THE SCRIPPS RESEARCH INSTITUTE | 2021-03-25 | — | — | US | disclosed |
| CN-112312902-A | Pd (II) -catalyzed enantioselective C-H arylation of free carboxylic acids | 斯克里普斯研究学院 | 2021-02-02 | — | — | CN | disclosed |
| WO-2019204477-A1 | PD(II)-CATALYZED ENANTIOSELECTIVE C-H ARYLATION OF FREE CARBOXYLIC ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-10-24 | — | — | WO | disclosed |
| EP-1597223-A2 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004067489-A2 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2004-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021427-B2 | Pd(II)-catalyzed enantioselective C—H arylation of free carboxylic acids | PDCD1, PDK3, PDCD1LG2 | TBXAS1 3447/4885CYP4F2 1788/4885CYP4A11 1204/4885 |
| US-20210087131-A1 | PD(II)-CATALYZED ENANTIOSELECTIVE C-H ARYLATION OF FREE CARBOXYLIC ACIDS | PDCD1, PDK3, PDCD1LG2 | TBXAS1 3302/4885CYP4F2 1762/4885CYP4A11 1182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.