SCHEMBL6200593

SCHEMBL6200593

CC1CN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC(CC(N)=O)N1C(=O)c1ccc(-c2cc[n+]([O-])cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 18/20 0.41
F2 P00734 2/20 0.36
SLC6A7 Q99884 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6727755 0.94 F10 (0.42) F10F2
SCHEMBL6735008 0.94 F10 (0.42) F10F2
SCHEMBL6727759 0.94 F10 (0.42) F10F2
SCHEMBL6730851 0.85 F10 (0.37) F10F2
SCHEMBL6728225 0.84 F10 (0.39) F10
SCHEMBL6728220 0.84 F10 (0.39) F10
SCHEMBL6731737 0.83 F10 (0.45) F10F2
SCHEMBL6734414 0.83 F10 (0.45) F10F2
SCHEMBL6731741 0.83 F10 (0.45) F10F2
SCHEMBL6731743 0.83 F10 (0.45) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1031563-B1 SULFONYL DERIVATIVES DAIICHI SEIYAKU CO (JP) 2005-12-28 EP disclosed
US-20030232808-A1 Sulfonyl derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-12-18 US disclosed
US-6525042-B1 Inhibits an activated coagulation factor FXa; anticoagulant, antithrombotic DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-02-25 US disclosed
EP-1031563-A1 SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2000-08-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232808-A1 Sulfonyl derivatives SULT1E1, SULT2A1, SULT1A1 F10 76/4885F2 4/4885SLC6A7 4036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.