Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197529 | 0.87 | RXFP1 (0.47) | TP53RXFP1LMNAEPHX2KCNH2 | |
| SCHEMBL6200655 | 0.85 | KCNH2 (0.48) | TP53RXFP1LMNAKCNH2POLA1 | |
| SCHEMBL6195950 | 0.84 | LMNA (0.53) | TP53RXFP1LMNAMAPTMEN1 | |
| SCHEMBL6198169 | 0.83 | EGLN1 (0.49) | TP53LMNAKDM4EEGLN1POLA1 | |
| SCHEMBL6204261 | 0.82 | TP53 (0.45) | TP53RXFP1LMNAKDM4EEPHX2 | |
| SCHEMBL6200011 | 0.81 | KCNH2 (0.53) | TP53RXFP1KCNH2PPARGPOLA1 | |
| SCHEMBL6200361 | 0.81 | EGLN1 (0.47) | TP53LMNAEGLN1POLA1 | |
| SCHEMBL6200360 | 0.80 | TP53 (0.43) | TP53RXFP1LMNAEPHX2KCNH2 | |
| SCHEMBL6707890 | 0.80 | RXFP1 (0.52) | TP53RXFP1LMNAKDM4EKCNH2 | |
| SCHEMBL6202614 | 0.79 | EGLN1 (0.47) | TP53LMNAMEN1KMT2AEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |