Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 17/20 | 0.75 |
| ▸ | PGR | P06401 | 12/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4704272 | 0.91 | PGR (0.75) | NR3C1PGR | |
| SCHEMBL4704421 | 0.87 | PGR (0.71) | NR3C1PGR | |
| SCHEMBL4702557 | 0.86 | NR3C1 (1.00) | NR3C1PGR | |
| SCHEMBL4702886 | 0.85 | NR3C1 (1.00) | NR3C1PGR | |
| SCHEMBL4704667 | 0.84 | NR3C1 (1.00) | NR3C1PGR | |
| SCHEMBL4704899 | 0.83 | PGR (1.00) | NR3C1PGR | |
| SCHEMBL14099488 | 0.83 | NR3C1 (0.70) | NR3C1PGR | |
| SCHEMBL4704787 | 0.82 | PGR (1.00) | NR3C1PGR | |
| SCHEMBL4702457 | 0.81 | NR3C1 (1.00) | NR3C1PGR | |
| SCHEMBL4702860 | 0.80 | NR3C1 (1.00) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532113-A2 | SUBSTITUTED HIHYDROQUINOLINES AS GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2005-05-25 | — | — | EP | claimed |
| US-6858627-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-02-22 | — | — | US | claimed |
| US-20040116455-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | claimed |
| WO-2004018429-A2 | SUBSTITUTED HIHYDROQUINOLINES AS GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-03-04 | — | — | WO | claimed |
| US-6858627-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-02-22 | — | — | US | disclosed |