Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 3/20 | 0.70 |
| ▸ | ALPL | P05186 | 1/20 | 0.70 |
| ▸ | ALPG | P10696 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203056 | 0.87 | GCGR (0.72) | GCGRALPLALPGKMT2AMAPT | |
| SCHEMBL2649217 | 0.82 | GCGR (1.00) | GCGRALPLALPGKMT2AMAPT | |
| SCHEMBL30661861 | 0.82 | GCGR (1.00) | GCGRALPLALPGKMT2AMAPT | |
| SCHEMBL9261397 | 0.82 | MAPT (0.66) | GCGRALPLALPGKMT2AMAPT | |
| SCHEMBL12486648 | 0.81 | MPO (0.78) | KMT2AMAPTMEN1RAB9AALDH1A1 | |
| SCHEMBL14304382 | 0.80 | KMT2A (0.79) | GCGRALPLALPGKMT2AMAPT | |
| SCHEMBL12027518 | 0.80 | SMN1; SMN2 (0.79) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8251328 | 0.79 | KMT2A (0.77) | GCGRALPLALPGKMT2AMAPT | |
| SCHEMBL3515244 | 0.79 | KMT2A (1.00) | GCGRALPLALPGKMT2AMEN1 | |
| SCHEMBL29770390 | 0.79 | KMT2A (1.00) | GCGRALPLALPGKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |