SCHEMBL3515244

SCHEMBL3515244

O=C(O)CSc1nc2ccccc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 1.00
SMN1; SMN2 Q16637 4/20 0.66
HPGD P15428 1/20 0.66
RAB9A P51151 7/20 0.65
HSD17B10 Q99714 2/20 0.65
BCHE P06276 1/20 0.65
NPC1 O15118 6/20 0.64
POLB P06746 2/20 0.63
EPHX2 P34913 1/20 0.62
MEN1 O00255 1/20 0.61
HTT P42858 1/20 0.61
ALPL P05186 1/20 0.61
ALPG P10696 1/20 0.61
GCGR P47871 1/20 0.61
ALDH1A1 P00352 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
LMNA P02545 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29770390 1.00 KMT2A (1.00) KMT2ASMN1; SMN2HPGDRAB9AHSD17B10
SCHEMBL14304382 0.89 KMT2A (0.79) KMT2ASMN1; SMN2HPGDRAB9AHSD17B10
SCHEMBL4673914 0.88 KMT2A (0.78) KMT2ASMN1; SMN2HPGDRAB9AHSD17B10
SCHEMBL8251328 0.87 KMT2A (0.77) KMT2ASMN1; SMN2HPGDRAB9AHSD17B10
SCHEMBL15474114 0.86 KMT2A (0.75) KMT2ASMN1; SMN2HPGDRAB9AHSD17B10
SCHEMBL8797365 0.86 KMT2A (0.75) KMT2ASMN1; SMN2HPGDRAB9AHSD17B10
SCHEMBL10762447 0.84 KMT2A (0.73) KMT2ASMN1; SMN2HPGDRAB9AHSD17B10
SCHEMBL10890184 0.84 KMT2A (0.73) KMT2ASMN1; SMN2RAB9ABCHENPC1
SCHEMBL8425964 0.83 SMN1; SMN2 (0.79) KMT2ASMN1; SMN2HPGDRAB9AHSD17B10
SCHEMBL12485740 0.83 MPO (0.81) KMT2ASMN1; SMN2RAB9APOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114766506-B Chlorine dioxide disinfectant and preparation method and application thereof 广东环凯生物技术有限公司 2022-09-06 CN claimed
CN-114766506-A Chlorine dioxide disinfectant and preparation method and application thereof 广东环凯生物技术有限公司 2022-07-22 CN claimed
US-20240132479-A1 THERAPEUTIC COMPOUNDS AND USES THEREOF BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2024-04-25 US disclosed
CN-114766506-B Chlorine dioxide disinfectant and preparation method and application thereof 广东环凯生物技术有限公司 2022-09-06 CN disclosed
CN-114766506-A Chlorine dioxide disinfectant and preparation method and application thereof 广东环凯生物技术有限公司 2022-07-22 CN disclosed
EP-3611224-A1 COMPOSITION, COMPOSITE FILM AND MEMBRANE ELECTRODE ASSEMBLY ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-02-19 EP disclosed
US-20140275224-A1 CYTOSINE DEAMINASE MODULATORS FOR ENHANCEMENT OF DNA TRANSFECTION REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2014-09-18 US disclosed
WO-2013074059-A2 CYTOSINE DEAMINASE MODULATORS FOR ENHANCEMENT OF DNA TRANSFECTION REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2013-05-23 WO disclosed
US-8278327-B2 PDE10 inhibitors and related compositions and methods OMEROS CORPORATION (US) 2012-10-02 US disclosed
US-20120116027-A1 PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS NOVO NORDISK A/S (DK) 2012-05-10 US disclosed
CN-1709870-B Optical-purity N',N'-dibasic prolyl hydrazine compound, and its preparing method and use CHENGDU BIOLOGY INST CHINESE ACADEMY OF SCIENCES 2011-07-06 CN disclosed
WO-1995012590-A1 PREPARATION OF OMEPRAZOLE AND LANSOPRAZOLE AND INTERMEDIATES USEFUL THEREIN TORCAN CHEMICAL LTD. (CA) 1995-05-11 WO disclosed
US-5374730-A Preparation of omeprazole and lansoprazole TORCAN CHEMICAL LTD. (CA) 1994-12-20 US disclosed
US-4762848-A IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1988-08-09 US disclosed
EP-0194572-A1 Heterocyclic sulfides, process for their preparation and Medicaments containing them HOECHST AKTIENGESELLSCHAFT (DE) 1986-09-17 EP disclosed
US-4528286-A Method of using certain aryl-mercapto-lower-alkanamides as antiseborrheic agents HENKEL KOMMANDITGESELLSCHAFT (KGAA) (DE) 1985-07-09 US disclosed
EP-0128862-A2 Anti-corrosive coating composition CIBA-GEIGY AG (CH) 1984-12-19 EP disclosed
EP-0006347-B1 COMPOSITIONS AND METHOD FOR REGULATING SOYBEAN PLANT GROWTH UTILIZING SUBSTITUTED BENZAZOLYLTHIOALKANOIC ACIDS MONSANTO COMPANY (US) 1984-01-25 EP disclosed
US-4391886-A Methine colorant materials and the use thereof in electrophoretic migration imaging layers and processes EASTMAN KODAK COMPANY (US) 1983-07-05 US disclosed
US-4304908-A Methine colorant materials and the use thereof in electrophoretic migration imaging layers and processes EASTMAN KODAK COMPANY (US) 1981-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120116027-A1 PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS GHRHR, GHITM, GHSR KMT2A 3404/4885SMN1; SMN2 4684/4885HPGD 1448/4885
US-20240132479-A1 THERAPEUTIC COMPOUNDS AND USES THEREOF CUTA, DCXR, PLOD3 KMT2A 2269/4885SMN1; SMN2 560/4885HPGD 4181/4885
US-20140275224-A1 CYTOSINE DEAMINASE MODULATORS FOR ENHANCEMENT OF DNA TRANSFECTION CDA, DCTD, ADA KMT2A 1471/4885SMN1; SMN2 2561/4885HPGD 1501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.