Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.61 |
| ▸ | ITGAV | P06756 | 2/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 3/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8387978 | 0.88 | FOLH1 (0.65) | ITGB3ITGAVFOLH1SIRT2SIRT1 | |
| SCHEMBL10421088 | 0.88 | FOLH1 (0.62) | ITGB3ITGAVFOLH1SIRT2SIRT1 | |
| SCHEMBL4173691 | 0.87 | FOLH1 (0.72) | ITGB3ITGAVFOLH1SIRT2SIRT1 | |
| SCHEMBL4173693 | 0.87 | FOLH1 (0.72) | ITGB3ITGAVFOLH1SIRT2SIRT1 | |
| SCHEMBL11875673 | 0.87 | FOLH1 (0.72) | ITGB3ITGAVFOLH1SIRT2SIRT1 | |
| SCHEMBL1162281 | 0.86 | SIRT2 (0.60) | ITGB3ITGAVFOLH1SIRT2SIRT1 | |
| SCHEMBL26654353 | 0.85 | TGM2 (0.68) | ITGB3ITGAVFOLH1SIRT2SIRT1 | |
| SCHEMBL26654355 | 0.85 | TGM2 (0.68) | ITGB3ITGAVFOLH1SIRT2SIRT1 | |
| Hydrochloric Acid SCHEMBL1162135 | 0.85 | SIRT2 (0.59) | ITGB3ITGAVFOLH1SIRT2SIRT1 | |
| SCHEMBL7515531 | 0.84 | FOLH1 (0.58) | ITGB3ITGAVFOLH1SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165532-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-01-12 | — | — | EP | disclosed |
| US-6503897-B1 | N-Formylhydroxylamine derivatives; veterinary medicine; grampositive and gramnegative bacteria | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2003-01-07 | — | — | US | disclosed |
| EP-1165532-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058294-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-10-05 | — | — | WO | disclosed |