Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.65 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.64 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.64 |
| ▸ | CTSL | P07711 | 2/20 | 0.60 |
| ▸ | CTSS | P25774 | 1/20 | 0.60 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.59 |
| ▸ | ITGAV | P06756 | 3/20 | 0.59 |
| ▸ | TGM2 | P21980 | 3/20 | 0.58 |
| ▸ | ECE1 | P42892 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.56 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10421088 | 0.97 | FOLH1 (0.62) | FOLH1SIRT2SIRT1CTSLCTSS | |
| SCHEMBL600823 | 0.94 | FOLH1 (0.60) | FOLH1SIRT2SIRT1CTSLCTSS | |
| SCHEMBL5711357 | 0.94 | FOLH1 (0.60) | FOLH1SIRT2SIRT1CTSLCTSS | |
| SCHEMBL26641195 | 0.94 | FOLH1 (0.60) | FOLH1SIRT2SIRT1CTSLCTSS | |
| SCHEMBL5711236 | 0.94 | FOLH1 (0.60) | FOLH1SIRT2SIRT1CTSLCTSS | |
| SCHEMBL19658555 | 0.94 | FOLH1 (0.60) | FOLH1SIRT2SIRT1CTSLCTSS | |
| SCHEMBL15968143 | 0.93 | ITGB3 (0.66) | FOLH1SIRT2SIRT1ITGB3ECE1 | |
| SCHEMBL11308449 | 0.93 | SIRT2 (0.74) | FOLH1SIRT2SIRT1CTSLCTSS | |
| SCHEMBL9828826 | 0.93 | FOLH1 (0.69) | FOLH1SIRT2SIRT1CTSLCTSS | |
| SCHEMBL287475 | 0.93 | ITGB3 (0.66) | FOLH1SIRT2SIRT1ITGB3ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775104-B1 | DIMER DTPA DERIVATIVES AND THEIR METAL COMPLEXES, PHARMACEUTICALS CONTAINING THE SAME, THEIR USE IN DIAGNOSIS AND THERAPY AND PROCESS FOR PREPARING SAID COMPLEXES AND PHARMACEUTICALS | SCHERING AG (DE) | 1999-05-06 | — | — | EP | disclosed |
| US-5695737-A | CONTRAST MEDIA FOR NUCLEAR MAGNETIC RESONANCE | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |
| EP-0775104-A1 | DIMER DTPA DERIVATIVES AND THEIR METAL COMPLEXES, PHARMACEUTICALS CONTAINING THE SAME, THEIR USE IN DIAGNOSIS AND THERAPY AND PROCESS FOR PREPARING SAID COMPLEXES AND PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005167-A1 | DIMER DTPA DERIVATIVES AND THEIR METAL COMPLEXES, PHARMACEUTICALS CONTAINING THE SAME, THEIR USE IN DIAGNOSIS AND THERAPY AND PROCESS FOR PREPARING SAID COMPLEXES AND PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-02-22 | — | — | WO | disclosed |