Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 19/20 | 0.72 |
| ▸ | ITGB2 | P05107 | 18/20 | 0.72 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.72 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091330 | 0.94 | ITGAL (0.81) | ITGALITGB2ICAM1 | |
| Trifluoroacetic Acid SCHEMBL27689457 | 0.92 | ITGAL (0.69) | ITGALITGB2ICAM1 | |
| SCHEMBL5830196 | 0.86 | ITGAL (0.82) | ITGALITGB2ICAM1PLA2G4A | |
| SCHEMBL5829931 | 0.84 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL5830841 | 0.82 | ITGAL (0.77) | ITGALITGB2ICAM1PLA2G4A | |
| SCHEMBL5830363 | 0.82 | ITGAL (0.79) | ITGALITGB2ICAM1 | |
| SCHEMBL7621048 | 0.82 | ITGAL (0.79) | ITGALITGB2ICAM1 | |
| SCHEMBL6498764 | 0.81 | ITGAL (0.75) | ITGALITGB2ICAM1 | |
| Trifluoroacetic Acid SCHEMBL6201123 | 0.81 | ITGB2 (0.47) | ITGALITGB2ICAM1PLA2G4A | |
| SCHEMBL7619718 | 0.81 | ITGAL (0.80) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250768-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2005-11-10 | — | — | US | disclosed |
| EP-1140814-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2005-05-25 | — | — | EP | disclosed |
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | disclosed |
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250768-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ICAM1, VCAM1, EPCAM | ITGAL 57/4885ITGB2 32/4885ICAM1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.