Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.60 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7845700 | 0.84 | NHERF1 (0.61) | ADORA2AADORA1NHERF1POLBMAPT | |
| SCHEMBL6230550 | 0.84 | NHERF1 (0.68) | ADORA2AADORA1NHERF1POLBMAPT | |
| SCHEMBL7842334 | 0.83 | NHERF1 (0.58) | ADORA2AADORA1NHERF1POLBMAPT | |
| Hydrochloric Acid SCHEMBL6206076 | 0.83 | NHERF1 (0.67) | ADORA2AADORA1NHERF1POLBMAPT | |
| SCHEMBL7834823 | 0.83 | NHERF1 (0.60) | ADORA2AADORA1NHERF1POLBMAPT | |
| SCHEMBL6818435 | 0.82 | POLB (0.67) | ADORA2AADORA1NHERF1POLBSMN1; SMN2 | |
| SCHEMBL6205349 | 0.82 | NHERF1 (0.65) | ADORA2AADORA1NHERF1POLBMAPT | |
| SCHEMBL6204128 | 0.81 | NHERF1 (0.68) | ADORA2AADORA1NHERF1POLBMAPT | |
| Hydrochloric Acid SCHEMBL6205703 | 0.80 | NHERF1 (0.63) | ADORA2AADORA1NHERF1POLBMAPT | |
| SCHEMBL6195763 | 0.78 | NHERF1 (0.58) | ADORA2AADORA1NHERF1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |