Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NHERF1 | O14745 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GABRP | O00591 | 3/20 | 0.52 |
| ▸ | GABRD | O14764 | 3/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.52 |
| ▸ | GABRE | P78334 | 3/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6205703 | 0.84 | NHERF1 (0.63) | NHERF1ADORA2AADORA1POLBMAPT | |
| SCHEMBL7845700 | 0.84 | NHERF1 (0.61) | NHERF1ADORA2AADORA1POLBMAPT | |
| SCHEMBL6230550 | 0.84 | NHERF1 (0.68) | NHERF1ADORA2AADORA1POLBMAPT | |
| SCHEMBL6201470 | 0.83 | ADORA2A (0.60) | NHERF1ADORA2AADORA1POLBMAPT | |
| SCHEMBL7834823 | 0.83 | NHERF1 (0.60) | NHERF1ADORA2AADORA1POLBMAPT | |
| Hydrochloric Acid SCHEMBL6206076 | 0.83 | NHERF1 (0.67) | NHERF1ADORA2AADORA1POLBMAPT | |
| SCHEMBL6670721 | 0.82 | NHERF1 (0.55) | NHERF1ADORA2AADORA1POLBMAPT | |
| SCHEMBL6818435 | 0.82 | POLB (0.67) | NHERF1ADORA2AADORA1POLBLMNA | |
| SCHEMBL6205349 | 0.82 | NHERF1 (0.65) | NHERF1ADORA2AADORA1POLBMAPT | |
| SCHEMBL6204128 | 0.81 | NHERF1 (0.68) | NHERF1ADORA2AADORA1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |